What type of study is this?

This is a Systematic Review study (also classified as: Case Report).

October 2, 2025Open Access

Implant Peri-apical Lesions: Literature Review and Two Case Reports

ZGZülal Deniz GünerAnkara University MAMurat AkkayaLokman Hekim Üniversitesi FKFatma KaracaoğluAnkara University

Key Points

Effective treatment approaches for implant peri-apical lesions include both periapical and regenerative surgery.
Case reports highlight two patients who experienced complications after implant surgery, with successful follow-up outcomes.
Surgical interventions involved removing granulation tissue and applying graft and membrane in one case to aid recovery.
The absence of complications post-treatment reinforces the efficacy of the methods employed in the case reports.

Abstract

Introduction: Implant peri-apical lesion is a peri-implant complication characterized by radiographic bone loss around the implant apex. Different approaches have been proposed for the treatment of implant peri-apical lesions, including periapical surgery and regenerative surgery with or without resection of the implant apex. Method: In this systematic review, we searched the available literature on implant apical lesions using the PubMed database and described the possible etiologies and treatments of two implant peri-apical lesions that occurred at different stages of osteointegration. Case Report: Two patients presented to our clinic with pain and swelling 16 days and 7 months after implant surgery. In both patients, the operation site was opened, granulation tissues were removed and the area was irrigated with sterile saline. In the second patient, graft and membrane application was performed additionally. Both sites were closed primerally. Conclusion: No complications were observed at either site during the follow-up period. Therefore, both approaches can be considered effective in the treatment of implant peri-apical lesions.

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