Analysis of vitamin D availability in patients with irritable bowel syndrome of various etiologies

Objective: to analyze vitamin D availability in patients with irritable bowel syndrome of various etiologies. Materials and methods: 148 patients with irritable bowel syndrome with a predominance of diarrhea were examined. Group I included 88 patients with irritable bowel syndrome after COVID-19; group II included 60 patients in whom the disorder was stress–induced. The control group included 30 relatively healthy subjects. Vitamin D availability was assessed for all participants. Results: an analysis of vitamin D provision in patients suffering from irritable bowel syndrome showed a predominance of patients with reduced levels of this micronutrient. In both groups of patients with irritable bowel syndrome, the incidence of vitamin D deficiency was significantly higher than in the control group. Thus, in group I, a decrease in serum calcidiol levels was found in 63 (71.6 %) patients, which was statistically significantly (p < 0.001) higher than in the control group, and in group II — in 24 (40.0 %) patients (p < 0.01), where the disorder was induced by stress. Conclusions: patients with irritable bowel syndrome are characterized by an insufficient supply of vitamin D. At the same time, this imbalance is more typical for patients who have developed IBS against the background of a new coronavirus infection.