Ayurveda, an ancient science of life, demands a research approach aligned with its personalized and holistic principles. This study reviews classical and modern methodologies applicable to Ayurvedic research while emphasizing ethical considerations. It highlights the need for non-conventional designs like N-of-1 trials, prakriti-based stratification, and participatory models. The integration of Ayurvedic epistemology with modern evidence-based frameworks remains a challenge but is vital for global validation. Ethical issues like consent, confidentiality, and community inclusion must be tailored to traditional systems. Strengthening institutional ethical practices and harmonizing ancient knowledge with scientific methods are essential steps forward.
Biradar et al. (Wed,) studied this question.