Outcomes of Patients with Trisomy 13 and 18 in a Center with a Dedicated Perinatal Palliative Care Program

Abstract Introduction:The objective of this study is to assess outcomes of pregnancies complicated by trisomy 13(T13) or trisomy 18(T18) and infants with T13 and T18, who were managed in a center with a perinatal palliative care program. Methods:This is a single center retrospective cohort study of neonates with T13 or T18 and pregnancies complicated by T13 or T18 in which families opted to continue the pregnancy, that were followed at Columbia University Irving Medical Center(CUIMC) between 2008-2024. Results:There were 109 pregnancies that resulted in 68 liveborn infants. Of those who met with the Neonatal Comfort Care Program(NCCP) prior to delivery, 69.9% opted for comfort care. There was no trend toward more intervention over a span of 17 years. Discussion:Consistency of consulting practices by the NCCP at CUIMC is reflected in the lack of trend toward more intervention in patients with T13 and T18 which has been reported in other institutions.