Who determines the outcome? A three-level meta-analysis on systemic therapy in children and adolescents

Key Points

• Systemic therapy improves symptoms across various outcome domains in children and adolescents, but effects are varied.
• The analysis highlights significant differences based on assessment methods, revealing nuances in treatment efficacy.
• Using a three-level meta-analysis, the study synthesized results to clarify systemic therapy's impact on different demographics.
• Findings suggest that informants play a critical role in determining therapy outcomes, calling for tailored assessment strategies.

Abstract