Effect of Fetal Brain Oxygenation and Volume on Brain Maturation and Neurodevelopmental Outcomes in Congenital Heart Disease

Key Points

• Neurodevelopmental outcomes were influenced by fetal brain volume, linking larger volumes to improved language skills.
• Poorer motor skills correlated with greater complexity of brain lesions, indicating potential areas for intervention.
• No significant relationship was found between fetal brain oxygenation and brain maturation or neurodevelopment.
• Congenital heart disease presented specific challenges that affected early brain development and later outcomes.