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October 9, 2025

Recurrent Multifocal Giant Cell Tumor of Tendon Sheath of the 5th Finger Flexor Digitorum Profundis Tendon: A Case Report

KCKirsten ChristoffersenUniversity of Copenhagen ABAnia BartholomewLake Erie College of Osteopathic Medicine MMMichael C. McDermottFranciscan Health

Key Points

Four separate giant cell tumors along the flexor digitorum profundus were surgically removed, but recurrence occurred after fifteen weeks.
Histological examination confirmed the diagnosis of giant cell tumor of tendon sheath, a rare multifocal presentation.
Surgical removal was followed by a thorough post-operative assessment to monitor for recurrence and complications.
Highlights the need for careful monitoring in patients with multifocal giant cell tumors due to high recurrence rates.

Abstract

Giant cell tumors of the tendon sheath (GCTTS) typically present as discrete, solitary nodules along a tendon near the joints in the fingers and toes. Multifocal GCTTS along a single tendon is a rare entity in which only a handful of cases have been described. In this article, we present a case of GCTTS in which four separate lesions along the flexor digitorum profundus (FDP) were surgically removed and then recurred fifteen weeks later on the fifth finger of the same hand. This report characterizes the presentation of a GCTTS, the surgical removal, and the post-operative course for this patient.

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