October 12, 2025

Ketamine cuts suicidality‐linked ER visits in TRD patients

Key Points

Ketamine treatment led to a significant reduction in ED visits related to suicidality.
The study revealed a notable decline in suicidality-associated ED utilization.
Mirror-image analysis tracked changes before and after ketamine or esketamine treatment.
These findings suggest that ketamine may serve as a crucial option for reducing suicidality in TRD patients.

Abstract

A new study published in the Journal of Clinical Psychiatry suggests that ketamine and esketamine may significantly reduce emergency department (ED) visits related to suicidality in individuals with treatment‐resistant depression (TRD). The six‐month mirror‐image study tracked patients before and after receiving acute treatment with either ketamine or esketamine, revealing a striking decline in suicidality‐associated ED utilization.

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Valerie A. Canady (Fri,) studied this question.

synapsesocial.com/papers/68ec1be02b8fa9b2b78ad0a2 — DOI: https://doi.org/10.1002/mhw.34618

Ketamine cuts suicidality‐linked ER visits in TRD patients

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