Introduction: Human Papillomavirus (HPV) remains a leading cause of cervical cancer and is a major public health concern, especially in low- and middle-income countries like India. While effective vaccines exist, awareness and acceptance remain low. In Kerala, where literacy is high, little is known about the knowledge, attitudes, and practices (KAP) surrounding the HPV vaccine among adolescents, their parents, and teachers. This cross-sectional study will include Methods And Analysis: school children aged 11–15 years, their parents, and teachers in Thiruvalla Municipality, Kerala. Stratified random sampling will be used for student selection from four schools representing government, aided, and private sectors. Census sampling will include all eligible teachers, and parents will be recruited via convenience sampling. A structured, validated questionnaire will be used. Data will be analyzed using descriptive statistics, t-tests, chi-square tests, and logistic regression to explore associations and predictors of KAP. Ethical cl Ethics And Dissemination: earance has been obtained. Permissions from school authorities are being secured. When participant data will be collected, consent to participate will be taken from each participant. Findings will be disseminated through scientific publications, presentations, and community outreach. Clinical Trial Registration : Not applicable (observational study). Strengths and Limitations of This Study First study in Kerala examining HPV vaccine KAP among all three key stakeholder groups.Multistakeholder approach offers a comprehensive understanding of barriers and enablers. Data will inform tailored health education programs in schools. Cross-sectional design limits causal inference. Parent participation through convenience sampling may introduce selection bias.
John et al. (Wed,) studied this question.