Background and aim Cystic ovarian lesions are more prevalent in adolescents due to the initiation of hormonal activity during prepubescence. We aimed to evaluate diagnostic accuracy of ultrasound and tumors markers in diagnosis of complex ovarian cysts in adolescents with histopathological correlation. Patients and methods This prospective cohort investigation has been carried out on 300 adolescent cases diagnosed with ovarian cysts who were attended to the outpatient clinic and emergency room of the obstetrics and gynecology department of Al-Azhar University Hospital (Assiut). The diagnoses of ovarian cysts were made inside or outside the hospital. In cases where the diagnosis was made outside the hospital, we confirmed it inside the hospital. Results Ultrasound was with higher sensitivity and specificity 87% and 84% correspondingly. Tumor markers were with lower sensitivity and specificity 84 and 80%, respectively. Ultrasound detected 92.5% of dermoid cyst, 85% of endometriomas, 87.5% of serous cystadenomas, 66% of mucinous cystadenoma, 100% of juvenile granulosa cell tumor, and 100% of immature teratoma. Conclusion Regarding the results of this study, the ultrasound was with sensitivity and specificity 87 and 84% respectively, and tumor markers were with sensitivity and specificity 84 and 80% respectively. The study concluded that ultrasound was more important in screening for complex ovarian cysts in adolescents and adding cancer indicators is essential for diagnosis or to exclude the ovarian malignancy and combined both increases the sensitivity, specificity, positive and negative predictive value, and accuracy.
saedy et al. (Tue,) studied this question.
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