This article reviews the basic mechanisms of normal and abnormal cardiac impulse propagation, including structural determinants, conduction block, and re-entry mechanisms.
Abstract The sections in this article are: Basic Mechanisms of Cardiac Impulse Propagation The Continuous Cable Two‐Dimensional Propagation and Wavefront Curvature Structural Determinants of Anisotropic and Discontinuous Conduction Propagation in Discontinuous Structures Discontinuous Propagation in a Cell Chain and a Cell Strand Anisotropic Propagation The Electrical Resistance of the Extracellular Space The Bidomain Behavior of Cardiac Tissue The Activation of the Whole Heart—from the Sinus Node to the Ventricles The Sinus Node—Spread of Excitation from the Sinus Node to the Atrium Disturbances of Impulse Conduction and Conduction Block The Safety Factor of Propagation Effects of Changes in Resting Membrane Potential and Inhibition of Na + Channels on Conduction Velocity Conduction Slowing and Block: The Role of Ca ++ Inward Current Conduction Slowing and Discontinuous Conduction Mechanisms of Unidirectional Block Circulating Excitation, Re‐Entry, and Spiral Waves Anatomic Re‐entry Functional Re‐entry—the Leading Circle Concept Spiral Wave Re‐entry Transition from Functional to Anatomic Re‐entry. Anchoring of Spiral Waves
Kléber et al. (Sun,) conducted a review in Cardiac conduction abnormalities. This article reviews the basic mechanisms of normal and abnormal cardiac impulse propagation, including structural determinants, conduction block, and re-entry mechanisms.
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