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Bioprinting represents the transformative approach to additive manufacturing, specifically in fabricating scaffolds and tissue constructs. While notable advancements have been made in fabricating organ tissues and neural tissues, challenges persist regarding optimized printability conditions, mechanical properties, and cell viability. This study uniquely integrates computational fluid dynamics (CFD) and finite element analysis (FEA) to refine bioprinting parameters and enhance scaffold performance. Advanced bio-printed techniques are investigated for their ability to produce high precision and improved cell viability. The main objective of this study is to present a simulation-driven approach to bioprinting that refines both biological and mechanical properties. A discussion is conducted about the bioprinting methods and the simulation conditions employed to optimize the outcomes of the bioprinting process. Additionally, applications of bioprinting in various fields are presented. Conclusively, integrating simulation techniques with bioprinting enhances mechanical properties and cell viability, accelerating innovation in bioprinting.
Madem et al. (Mon,) studied this question.