Abstract Background and Aims Methamphetamine use disorder (MUD) is associated with significant impairments in impulsivity control, contributing to relapse and poor treatment outcomes. Transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) may be helpful in modulating these symptoms. This study aimed at 1 investigating the differential effects of anodal and cathodal tDCS on craving, affective impulsivity, and motor impulsivity; and 2 exploring the correlations between changes in affective impulsivity cathodal: estimate = 2.62, 95% CI 0.34, 4.9, p = 0.02). Changes in affective impulsivity were statistically significantly correlated with alterations in Rs‐EEG microstate parameters, such as microstate B coverage (r = 0.29, p. < 0.01, n = 100); however, there is a lack of clear evidence for correlations between changes in craving and microstate parameters. Conclusions Among methamphetamine users in rehabilitation, anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex appears to improve affective impulsivity control, but not motor impulsivity control, and both anodal and cathodal tDCS reduce drug craving.
Jiang et al. (Wed,) studied this question.
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