Oncofetal chondroitin sulfate in cancer therapy: a promising target for anti-tumor drug delivery?

Key Points

• The aim is to evaluate the potential of oncofetal chondroitin sulfate in cancer therapy as a drug delivery target.
• Discussed the role of oncofetal chondroitin sulfate in cancer
• Explored its interactions within the tumor microenvironment
• Analyzed its impact on tumor-associated carbohydrates and stroma.
• Found that oncofetal chondroitin sulfate could enhance the effectiveness of antibody-based therapies in cancer.
• Indicated that targeting this molecule may improve drug delivery efficiency in the tumor stroma.

Abstract