What question did this study set out to answer?

To identify risk factors associated with ventricular arrhythmia following recovery of ventricular function.

January 10, 2026Open Access

Risk Stratification for Ventricular Arrhythmia Following Ventricular Function Recovery

Key Points

To identify risk factors associated with ventricular arrhythmia following recovery of ventricular function.
Conducted an observational cohort analysis

Structured PICO

Does incorporating ventricular function recovery improve risk stratification for sudden cardiac death and appropriate ICD therapy in heart failure patients compared to relying solely on baseline LVEF?

Population

Heart failure patients considered for primary prevention implantable cardioverter-defibrillator (ICD) therapy in Japan

Intervention

Risk stratification incorporating ventricular functional recovery (LVEF improvement to ≥35%) and structural information

Comparator

Current criteria relying solely on baseline LVEF <35% and non-sustained ventricular tachycardia (NSVT)

Outcome

Sudden cardiac death and appropriate ICD therapieshard clinical

Relying solely on baseline LVEF to guide primary prevention ICD implantation is insufficient; incorporating LVEF improvement offers a complementary approach to refine patient selection and risk stratification.

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