Advancing total synthesis through the Stille cross-coupling: recent innovations and case studies | Synapse
January 14, 2026Open Access
Advancing total synthesis through the Stille cross-coupling: recent innovations and case studies
Key Points
To explore how innovations in the Stille reaction have enhanced total synthesis processes.
Discussed recent innovations in Stille cross-coupling techniques.
Highlighted case studies demonstrating applications in total synthesis.
Reviewed advancements in the synthesis of complex natural products.
Enhanced efficiency in the total synthesis of pharmaceuticals.
Successful application of the Stille reaction in producing functional materials.
Demonstrated case studies exemplifying complex natural product synthesis.
Abstract
The Stille reaction, a pivotal palladium-catalyzed cross-coupling, continues to drive advancements in the total synthesis of highly complex natural products, pharmaceuticals, and functional materials.