LVAD support in selected patients with non-ischemic cardiomyopathy may enable myocardial recovery and successful device explantation, providing an alternative to transplantation.
1 patient, 52-year-old male with advanced heart failure due to myocarditis, severely reduced ejection fraction of 23%, moderate diastolic dysfunction, severe functional mitral regurgitation, and inotrope-dependence.
Left ventricular assist device (LVAD HeartMate II) implantation followed by decommissioning (pump left in situ, driveline cut, outflow graft surgically closed) after 3 years of support and reverse remodeling.
Clinical stability and preserved LV systolic function at 5-year follow-up.
LVAD decommissioning is a viable strategy for selected patients with non-ischemic cardiomyopathy who experience significant reverse remodeling, offering an alternative to heart transplantation.
Left ventricular assist devices (LVAD) improve clinical outcomes in patients with advanced heart failure (HF), including those with acute refractory HF. In carefully selected patients, depending on HF etiology, duration of HF, and degree of end-organ dysfunction, LVAD support may induce profound reverse structural remodeling and even functional myocardial recovery, ultimately permitting LVAD explantation. This “bridge to recovery” strategy, although conceptually appealing and clinically transformative, remains underutilized. Here, we present a case demonstrating that this strategy offers a valuable alternative to transplantation and highlights the importance of standardized protocols in identifying and managing LVAD recovery candidates.
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Sabina Ugovšek
Ivan Knežević
Gregor Poglajen
Srce i krvni sudovi
Ljubljana University Medical Centre
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Ugovšek et al. (Wed,) reported a other. LVAD support in selected patients with non-ischemic cardiomyopathy may enable myocardial recovery and successful device explantation, providing an alternative to transplantation.
www.synapsesocial.com/papers/696b25cfd2a12237a9349209 — DOI: https://doi.org/10.5937/siks2502031u