Background Contrast sensitivity is the ability of the eye to detect small changes in illumination at targets that do not have clearly defined limits. Amblyopia is a disorder of sight in which the brain fails to process inputs from one eye and over time favors the other eye. Refractive amblyopia is caused by anisometropia (difference of a certain degree of myopia, hypermetropia, or astigmatism), or by a significant amount of equal refractive error in both eyes. Visual-evoked potential/response (VEP) measures the electrical signal generated at the visual cortex in response to visual stimulation. Objectives The efficiency of contrast sensitivity, in comparison to VEP, regarding patients with anisometropic amblyopia. Patients and methods This is a cross-sectional study carried out on 78 patients with anisometropic amblyopia aged 4.5–12 years. All patients presented with monocular amblyopia. Contrast sensitivity tests and pattern VEPs were carried out for both eyes. Results The contrast sensitivity test showed decreased values in the amblyopic eye compared to the fellow eye. Meanwhile, P100 latency showed increases in the amblyopic eye and a decrease in amplitude compared to the fellow eye. Conclusion Contrast sensitivity tests could be used to assess the prognosis of patients with anisometropic amblyopia.
Salmawy et al. (Thu,) studied this question.