What is the clinical evidence from this study?

Study design: Cohort. Population: Partial and Transitional Atrioventricular Septal Defects (n=136). Intervention: Surgical repair vs. null. Primary outcome: Reoperation rate.

What question did this study set out to answer?

This research aims to assess the mid-term surgical outcomes for patients undergoing repair of partial and transitional atrioventricular septal defects (AVSDs).

February 2, 2026Open Access

Repair of Partial and Transitional Atrioventricular Septal Defects: Mid-term Outcomes in a Single-center Cohort

Key Result

Surgical repair of partial and transitional A VSDs results in excellent mid-term survival and a low reoperation rate of 2.9%.

Key Points

This research aims to assess the mid-term surgical outcomes for patients undergoing repair of partial and transitional atrioventricular septal defects (AVSDs).
Retrospective review of patients undergoing AVSD surgical repair from January 2019 to December 2022.
Assessment of key outcomes including mortality, reoperation rates, and AV valve repair strategies during follow-up.
Inclusion of both pediatric and adult patients with partial and transitional AVSDs.
A total of 136 patients underwent surgical repair with a median follow-up of 50.5 months.
No early or late mortality was recorded during the follow-up period.
Reoperation was necessary in 4 patients (2.9%), all related to left atrioventricular valve issues.
No significant differences in reoperation rates were found between AVSD subtypes or age groups.

Study Design

Type

Cohort (n=136)

Multicenter

Structured PICO

Does surgical repair of partial and transitional AVSDs result in favorable mid-term survival and low reoperation rates in pediatric and adult patients?

Population

136 patients with partial (n=100) or transitional (n=36) atrioventricular septal defects (AVSD) who underwent primary surgical repair, median age 22 years, 67.6% female. Excluded: concomitant complex congenital heart defects, primary repair at outside institutions, and pulmonary vascular resistance > 5 Wood units.

Intervention

Surgical repair of partial and transitional AVSDs, including closure of primum ASD, closure of restrictive VSD (for transitional), closure of LAVV zone of apposition, and tailored AVV valvuloplasty (suture or ring annuloplasty).

Outcome

Mid-term outcomes including mortality, reoperation, and atrioventricular valve (AVV) repair strategies assessed during follow-up.hard clinical

Surgical repair of partial and transitional AVSDs provides excellent mid-term survival (100%) and low reoperation rates (2.9%) across both pediatric and adult populations.

Limitations

Operator-dependent echocardiographic assessments may introduce variability in results.

Abstract

Background: Surgical repair of partial and transitional atrioventricular septal defects (AVSDs) aims to achieve optimal outcomes with minimal need for reintervention. This study aimed to evaluate the mid-term outcomes of AVSD repair in both pediatric and adult populations. Methods: We retrospectively reviewed all patients who underwent surgical repair for partial or transitional AVSDs at our center between January 2019 and December 2022. Key outcomes, including mortality, reoperation, and atrioventricular valve (AVV) repair strategies, were assessed during follow-up. Results: A total of 136 patients were included (partial AVSD, n = 100; transitional AVSD, n = 36), with a median follow-up of 50.5 months. The median hospital stay was 14 days. No early or late deaths occurred. Reoperation was required in four patients (2.9%); all reoperations included left atrioventricular valve (LAVV) reoperation. However, reoperation rates did not differ significantly between AVSD subtypes (p = 1.000) or age groups (p = 0.177). The incidence of moderate or greater LAVV regurgitation showed no significant difference between patients with and without ring annuloplasty, either postoperatively or at the final follow-up (both p = 1.000). Conclusions: Surgical repair of partial and transitional AVSDs results in excellent mid-term survival and a low reoperation rate across both pediatric and adult patients. Continued refinement of AVV repair strategies remains essential to reduce the risk of LAVV reintervention and prevent left ventricular outflow tract obstruction. Long-term follow-up is warranted to improve the evaluation of the durability of techniques such as suture annuloplasty and ring annuloplasty.

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