Establishing oncological safety of autologous fat transfer for total breast reconstruction: Results from the multicentre BREAST-I and BREAST-II trials

Key Points

• Autologous fat transfer for reconstruction shows no negative effect on mortality after mastectomy, indicating oncological safety.
• Follow-up analysis demonstrated comparable mortality rates between patients receiving autologous fat transfer and national registry controls.
• Multicentre cohort analysis included long-term follow-up to assess the implications of autologous fat transfer on overall health outcomes.
• Future research should involve larger cohorts to more rigorously evaluate disease-free survival outcomes.