An Open Label Randomised Comparative Clinical Study to Evaluate the Efficacy of Janu Basti Followed by Panchatikta Ksheera Basti and Atasi Upanaha Followed by Panchatikta Ksheersa Basti in the Management of Janusandhigata Vata W.S.R to Osteoarthritis of Knee Joint

Background: Janusandhigata Vata is one among the Vata Vyadhi in all the Samhitas, characterized by Shoola, Shotha, Stambha, Atopa, and Prasarana Akunchana Vedana in Janusandhi. Acharyas have recommended Snehana, Swedana, Bandhana, Upanaha, Agnikarma and Basti Karma as one of the treatment modalities for disease pertaining to Snayu, Asthi, and Sandhi. In this study, Snigdha Swedana and Upanaha is followed whereas in Asthigata vata chikitsa. Tikta ksheera basti is mentioned to get qualified result Panchatikta ksheera basti is adopted. Methodology: In the present study, 40 subjects were diagnosed as Janusandhigata Vata were randomly assigned into two groups, Group A and Group B, comprising 20 subjects each. Subjects belonging to Group A were subjected to Janu Basti with Moorchita Taila for the duration of 30 minutes, Panchatikta ksheera basti in the form of Yoga Basti pattern was administered for 8 consecutive days, whereas the subjects pertaining to Group B were subjected to Atasi Upanah and Panchatitka ksheera Basti in the form of Yoga Basti pattern for the duration of 12 hours a day, for 8 consecutive days. Results: In both Group A and Group B, the Wilcoxon Signed Rank Test applied within the group analysis for the subjective parameters has shown statistically highly significant results (P < 0.001). The Mann-Whitney ‘U’ Test applied between the group analysis for the subjective parameters has shown no significant difference between the two groups. Conclusion: The present study showed statistically significant result in both the Groups, based on mean rank Group B has an edge over a Group A.