Swedahara Pradeha, a class of topical Ayurvedic formulation, plays an essential role in the management of disorders characterized by excessive sweating (Atisweda), burning sensation (Daha), and Pitta vitiation. While their clinical use is well documented in classical Ayurvedic texts, the underlying mechanism of action remains less explored in modern scientific terms. This review attempts to correlate the Ayurvedic concept of Swedahara Pradeha with modern understanding of sweat gland physiology and thermoregulation. The study explores classical references, probable pharmacodynamic actions, and potential mechanisms through which these formulations may modulate sweating—such as local vasoconstriction, astringent effects, anti-inflammatory actions, and reduction of local heat. The integrative understanding developed through this review may help standardize and rationalize the use of Swedahara Pradeha in modern clinical contexts.
*1Dr. Vinay Bhardwaj, 2Dr. P. C. Mangal, 3Prof. (Dr.) S. R. Inchulkar (Sun,) studied this question.