What question did this study set out to answer?

To improve medical image classification while preserving patient confidentiality using federated learning methods.

February 5, 2026

Knowledge-Constrained Federated Learning for Medical Image Classification with SE-ResNeXt-50

DCD. Chandraprakash KSKhalid Nazim Abdul SattarMajmaah University KBKarunakara Rai BNitte University

Key Points

To improve medical image classification while preserving patient confidentiality using federated learning methods.
Utilized federated learning (FL) to train models without sharing sensitive medical data.
Implemented SE-ResNeXt-50 architecture for better feature extraction in medical imaging.
Evaluated the model on two datasets: BR35H for MRI images and SARS-CoV-2 CT scans.
Achieved 98.8% accuracy for MRI image classification.
Obtained 99.3% accuracy for CT scan classification.
Demonstrated improvement over existing CNN models with gray-level co-occurrence matrix.

Abstract

Recently, the classification of medical images plays an important role in healthcare, especially in diagnosing diseases and planning treatments. Advancements in intelligent systems operate in external or centralized environments concerning patient confidentiality, which is progressively essential. Traditional Machine Learning (ML) methods depend on data collection, which represents sensitive medical information and reduces the performance. To address this issue, Federated Learning (FL) is a suitable method that allows multiple institutions to collaboratively train models by incorporating knowledge constraints using their current data, without sharing confidential records. FL not only preserves privacy, but also supports robust and safe model development across various data sources. The proposed FL includes SE-ResNeXt-50, which combines the multibranch ResNeXt-50 design with a squeeze-and-excitation (SE) attention mechanism, allowing more discriminative feature extraction and adaptive channel weighting. The SE-ResNeXt-50 improves the models ability to handle heterogeneous and non-ID (non-identically distributed) medical imaging data across institutions. The proposed FL model integrating SE-ResNeXt-50 is evaluated using two different medical imaging datasets, BR35H (Brain Tumor Detection 2020) based on MRI images and SARS-CoV-2 CT on COVID-19, a lung CT scan image. The proposed FL model integrating SE-ResNeXt-50 achieves an accuracy of 98.8% for MRI images and 99.3% for CT scans, which is superior to the existing convolutional neural network (CNN) with the Gray-Level Co-occurrence Matrix (GLCM) model.

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