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PIKfyve is an essential component of the endolysosomal pathway within photoreceptors and the retinal pigment epithelium | Synapse
March 3, 2026
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PIKfyve is an essential component of the endolysosomal pathway within photoreceptors and the retinal pigment epithelium
KA
Karen Attia
University of Alberta
IA
Ifrah Anjum
University of Alberta
SL
Susanne Lingrell
University of Alberta
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Key Points
Key roles of PIKfyve indicate its essential function in cellular processes.
The analysis identifies distinct mechanisms of how PIKfyve operates in photoreceptors.
Examining the endolysosomal pathway highlights the significance of lipid metabolism.
Insights into PIKfyve's function call for further studies on retinal health.
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Attia et al. (Wed,) studied this question.
synapsesocial.com/papers/69a7600ec6e9836116a2c760
https://doi.org/https://doi.org/10.1016/j.exer.2026.110905