Abstract Introduction/Objective Penile surgeries, both for erectile dysfunction and for aesthetic purposes, have shown cyclical patterns in popularity, and their outcomes have often been controversial. Understanding the anatomical disposition of the dorsal neurovascular bundle at the level of the penile crura may help explain the variability of these surgical results. Materials and Methods We analyzed histological findings of the corpora cavernosa from patients undergoing male-to-female gender reassignment surgery at Hospital de San José, with the aim of characterizing the anatomy of the dorsal neurovascular bundle at the penile crura and the relationship among the dorsal vein, artery, and nerve. A descriptive case series study was conducted, collecting specimens between January 2022 and February 2025. Hematoxylin–eosin and Van Gieson staining techniques were used. Results Twenty cases were analyzed; 5 were excluded due to the level of the histological section, leaving 15 suitable for evaluation. The most frequently observed arrangement was vein–nerve–artery in 8 cases (53.3%). In 4 cases (26.7%), a central vein was flanked by lateral arteries, with nerves lateral to the arteries. Two cases (13.3%) showed the variant artery–vein–nerve, and in 1 case (6.6%) the arrangement was artery–nerve–vein. Conclusions Anatomical variations of the dorsal neurovascular bundle of the penis are present in healthy specimens. These findings allow a more precise understanding of the neurovascular anatomy of the penile crura, which may contribute to the refinement of surgical techniques and potentially improve clinical outcomes. Financing No conflict.
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H A Aponte
J S Gonzalez
Freddy Alexander Rodriguez Rodríguez
The Journal of Sexual Medicine
Fundación Universitaria de Ciencias de la Salud
Hospital Universitario Infantil San José
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Aponte et al. (Sun,) studied this question.
www.synapsesocial.com/papers/698435b9f1d9ada3c1fb4d04 — DOI: https://doi.org/10.1093/jsxmed/qdag002.012