The acquisition mechanism of medical images differs from that of natural images, consequently enabling frequency-domain information to reveal deeper-level pathological features in medical image analysis. However, extracting the significant pathological features from diverse frequency domains remain a core challenge in medical image segmentation. In this paper, we proposed an efficient medical image segmentation network, called FDE-Net, that effectively utilizes frequency-domain information. First, a Low-Frequency Information Extraction Block (LFIEB) is designed to selectively enhance critical information in frequency-domain features, thereby extracting the most discriminative pathological features. Furthermore, for seamless integration of frequency-domain and spatial features, a Multi-head Perception Visual State Space (MPVSS) is adopted with structural optimizations implemented to significantly improve multi-scale spatial feature extraction capabilities. Finally, a U-shaped network architecture was constructed, incorporating the Context Focus Attention (CFA) module to more efficiently propagate shallow features to the decoder. We validate FDE-Net on three publicly available medical image datasets. On ISIC-2018, our method achieves 84.10% IoU and 91.29% DSC, surpassing UNet by 6.24% and 3.74%, respectively, while maintaining computational efficiency. Comprehensive ablation studies confirm the individual contributions of the LFIEB and MPVSS modules. These results demonstrate that FDE-Net effectively balances segmentation accuracy and computational efficiency, making it promising for clinical deployment.
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Daxin Chen
Jiahua Wu
Xuyao Zhang
Scientific Reports
Chinese Academy of Sciences
Institute of Automation
Xiamen University of Technology
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Chen et al. (Wed,) studied this question.
www.synapsesocial.com/papers/698692e89d267392364c99af — DOI: https://doi.org/10.1038/s41598-026-38093-7