Background Atopic dermatitis (AD) is a chronic, recurrent inflammatory skin disease with a complex etiology involving genetic, environmental, and immunologic factors. In recent years, the influence of diet on AD has attracted widespread attention. However, the relationship between dietary components and AD remains complex and requires further investigation. Methods Up until October 2024, a thorough literature search was conducted using the internet databases of Web of Science, Cochrane, PubMed, and Scopus. The following keywords were used in the search strategy: “Atopic Dermatitis,” “Nutrition,” “Nutrients,” “Dietary Factors,” “Fatty Acids,” “Vitamin,” “Mineral,” “Zinc,” “Iron,” “Nickel,” “Probiotics,” “Prebiotics,” “Synbiotics,” “Breastfeeding,” “Maternal Diet,” “Phytochemicals,” “Polyphenol,” “Mediterranean Diet,” “Vegan Diet,” “Plant‐Based Diet,” “Gluten,” “Food Allergies,” “Elimination Diets,” “Dietary Exclusion,” and “Food Elimination.” This review systematically evaluates the literature on the impact of various dietary and nutritional factors on AD. Results The prevention or management of AD may benefit from a number of nutritional factors, including fatty acids, vitamins, minerals, probiotics, prebiotics, synbiotics, phytochemicals, and gluten, as well as dietary patterns, including breastfeeding, the Mediterranean diet, vegan diets, and elimination diets. By enhancing skin barrier function, lowering inflammatory responses, and modifying immunological responses, these nutrients and dietary strategies may help prevent and manage AD. However, the evidence currently available to support generalized dietary interventions as standard treatment for AD is still insufficient. Conclusion There are still a lot of inconsistencies in the research on the relationship between nutrients and AD. This review aims to inform future research and clinical practice in the management of AD and explore the potential of nutritional interventions in managing AD.
Pan et al. (Thu,) studied this question.