Magnesium doped hydroxyapatite (Mg-HA) nanocomposites have garnered considerable attention in the field of orthopedic implants due to their biodegradability, mechanical properties that closely resembles those of natural bone, and its inherent antibacterial properties. This review explores the synthesis and antibacterial efficacy of Mg-based nanocomposites, with a particular focus on Mg-HA. Several studies have employed microwave-assisted wet chemical synthesis to produce Mg-HA nanofibers, which have demonstrated exceptional antibacterial performance against common pathogens such as Staphylococcus aureus and Escherichia coli. While challenges such as rapid corrosion and potential Mg-ion toxicity remain, advancements in alloying techniques and surface treatments make Mg-based nanocomposites promising alternatives to conventional titanium implants. This dual functionality in promoting bone regeneration while preventing microbial infection helps in showcasing Mg-HA nanocomposites as promising materials for clinical bone repair.
Kurian et al. (Sat,) studied this question.