Increase in anthropogenic activities, and rapid industrialization have led to the release of effluents which consists of severe constituents that may lead to threat to the environment and its components. Endocrine-disrupting chemicals (EDCs) are a broader group of exogenous substances that can potentially hinder the endocrine networking in humans, animals, and even plants leading to adverse metabolic syndrome and malfunctioning of the system. They include chemicals such as bisphenol A (BPA), phthalates, pesticides, and industrial pollutants which can mimic, change or shut down the synthesis, metabolism, or action of hormones which are the prime signalling molecules for initiation of various metabolic pathways. It is a need for development of strategies to degrade these harmful chemicals for a sustainable environment and reduce their impacts on the ecosystem. The present review discusses the adverse effects of EDCs and elaborates the mechanism of biodegradation of EDCs from contaminated environment. The tripartite interaction amongst soil, plants and microbes has also been incorporated as it actually plays a significant role in the removal or neutralization of contaminants from environment. Lastly, the review throws light into the future perspectives and research scopes in the concerned area so that efficient removal techniques and monitoring methods can be developed for creating a sustainable environment.
Kaur et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: