What question did this study set out to answer?

To explore the relationship between retinal microvascular parameters and mild cognitive impairment in individuals with type 2 diabetes.

February 16, 2026Open Access

Testing the use of retinal microvascular parameters to identify individuals with type 2 diabetes with mild cognitive impairment

FPFrederik N. PedersenUniversity of Southern Denmark NLNoemi LoisQueen's University Belfast GBGeert Jan BiesselsUniversity Medical Center Utrecht

Key Points

To explore the relationship between retinal microvascular parameters and mild cognitive impairment in individuals with type 2 diabetes.
Analyzed retinal arteriolar tortuosity measurements
Evaluated discrimination ability of microvascular parameters
Correlated retinal findings with patient characteristics
Lower retinal arteriolar tortuosity linked to mild cognitive impairment
Microvascular parameters showed acceptable discrimination ability for identifying cognitive impairment

Abstract

In people with type 2 diabetes, a lower retinal arteriolar tortuosity was associated with MCI. In addition, we found retinal microvascular parameters to have an acceptable discrimination ability when paired with patient's characteristics.

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