Mechanochemical Synthesis of Aspirin Nanocrystals for Pharmaceutical Applications

Key Points

• The central aim is to enhance the bioavailability of aspirin using nanocrystal formulations.
• Mechanochemical synthesis was employed to create aspirin nanocrystals.
• Various formulations and conditions were tested to achieve optimal nanocrystal stability.
• Characterization of nanocrystal morphology was conducted to ensure uniformity.
• Nanocrystals exhibit improved stability compared to conventional aspirin formulations.
• Enhanced bioavailability was observed with the nanocrystal formulation, surpassing standard formulations.

Abstract