Abstract PS1-13-12: Our experience of using smooth tissue expanders in breast reconstruction

Abstract Introduction Breast reconstruction after mastectomy remains an urgent problem of modern mammoplasty. The use of tissue expanders allows for optimal aesthetic results with minimal risk of complications. Smooth expanders with an external port have now given way to expanders with an integrated port due to their installation features. However, there are a number of patients for whom, due to anatomical features, it is impossible to install an expander with an integrated port and a textured shell: due to the low "pinch" test and/or previous aggressive radiation therapy. In most cases, it is also difficult to use patchwork techniques for such patients. The purpose of the studyTo analyze the results of using smooth tissue expanders in complex breast reconstruction based on modern clinical data. Materials and methods A retrospective analysis of 78 clinical cases of the installation of smooth tissue expanders (expanders) from January 2023 to January 2025 was carried out. After radical mastectomy, smooth expanders with an external port with a volume from 300 ml to 700 ml were installed in patients. The complications (early and late), the analysis of aesthetic results, and the assessment of the quality of life of the patients were analyzed. Results The average duration of expansion was 6-8 weeks. The average expansion volume reached 500±100 ml. The success rate of the initial installation is 96.15%. The rate of early postoperative complications was 4.6%, and the rate of late complications was 2.8%. Early postoperative complications: seromas — 3.8% (3), suture failure - 2.6% (2). Late complications: expander protrusion - 2.6% (2), displacement of the external port - 5.1% (4). The average volume of the implant installed during expander replacement reached 450±50 ml. Conclusion According to our retrospective analysis, the use of smooth tissue expanders has advantages over textured counterparts.:- a significant reduction in early postoperative complications due to: a decrease in the frequency of seromas, infectious complications, and hematomas. We assume that the smooth surface of the endoprosthesis creates less mechanical injury to the tissue, and the surface of the endoprosthesis provides less contamination by bacteria.;- significant reduction in late postoperative complications: absence of malposition and rotation due to fixation of the posterior surface of the expander, absence of excessive fibrosis of the capsule due to the smooth surface;- The thinner expander capsule made it possible to install a larger implant than in the case of textured expanders, and the result was more aesthetic.;It is important to note that such expanders can be worn for longer, this is especially important, given the need to change the timing of breast reconstruction for various reasons. Citation Format: S. Abdugafforov, V. Vorotnikov, T. Mchedlidze, A. Gugnina, I. Kopytich, A. Soynov, M. Sharavina, M. Mukueva, S. Tsalko, D. Balayan, D. Romanov, E. Moiseyeva. Our experience of using smooth tissue expanders in breast reconstruction abstract. In: Proceedings of the San Antonio Breast Cancer Symposium 2025; 2025 Dec 9-12; San Antonio, TX. Philadelphia (PA): AACR; Clin Cancer Res 2026;32(4 Suppl):Abstract nr PS1-13-12.