Novel green-emissive carbon dots as a dual-purpose fluorometric tool for sensitive vismodegib detection and pharmacokinetic analysis

Key Points

• To develop and validate a dual-purpose fluorometric tool for sensitive detection of vismodegib and pharmacokinetic analysis.
• Synthesis of green-emissive carbon dots
• Optimization of fluorometric detection methods
• Assessment of vismodegib levels
• Analysis of pharmacokinetic parameters
• The developed tool shows high sensitivity in detecting vismodegib concentrations
• Pharmacokinetic analysis indicates improved drug monitoring capabilities
• Results align with required standards for therapeutic applications.

Abstract