Herein, we report a direct, visible light‐induced synthesis of quinoxalinones from diazoacetates and o ‐phenylenediamines under mild reaction conditions. This versatile protocol enables the controlled selective synthesis of 3,4‐dihydroquinoxalinones or quinoxalinones by tuning of acid–base conditions. In mechanistic studies, both singlet oxygen ( 1 O 2 ) generation and single‐electron transfer plays a crucial role in quinoxalinones synthesis. The gram‐scale synthesis of 3,4‐dihydroquinoxalinone and quinoxalinone affords a moderate yield, which proves the practicability of the reaction conditions.
Prasanth et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: