South Florida is the domestic epicenter of the HIV epidemic. However, awareness of and access to preexposure prophylaxis (PrEP) remain low. This report outlines lessons learned from the development and implementation of the PrEParados model-a spatially explicit, social network-based approach designed to engage adults in PrEP. Informed by social contagion theory, the PrEParados model integrates social network and geospatial methodologies to examine participant characteristics and gather information on their friendship, sexual, and substance use networks. (Am J Public Health. 2026;116(S1):S16-S21. https://doi.org/10.2105/AJPH.2025.308333).
Rodriguez et al. (Sun,) studied this question.