What does this research mean for the field?

Pandu Roga, characterized by pallor and linked to disturbances in the Tridosha, is associated with specific changes in red blood cell morphology indicative of various types of anemia. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to explore the connection between the Ayurvedic condition Pandu Roga and changes in RBC morphology.

March 1, 2026Open Access

The Integrative Study on Pandu Roga With Reference to RBC Morphology

Key Points

The aim is to explore the connection between the Ayurvedic condition Pandu Roga and changes in RBC morphology.
Analysis of classical Ayurvedic texts related to Pandu Roga.
Comparison with modern hematological findings on RBC morphology.
Identification of symptoms linked to different types of anemia.
Distinct changes in RBC morphology observed, including microcytosis and macrocytosis.
Symptomatology of Pandu Roga correlates with modern definitions of anemia.
Integration of Ayurvedic and biomedical perspectives enhances understanding of diagnosis and management.

Abstract

Pandu Roga is a significant condition mentioned in Ayurveda under Rasa-Rakta Duṣhṭi, where the key feature is pallor of the body. It develops due to weakened digestive fire, improper habits, and disturbance of the Tridosha primarily Pitta and Vata. Modern hematology links these symptoms to different types of anaemia, especially those marked by changes in red blood cell (RBC) morphology. Integrating Ayurvedic concepts with current biomedical insights helps enhance the understanding of its pathogenesis, diagnostic approach and management strategies. This article examines Pandu Roga based on classical Ayurvedic texts and aligns it with modern observations of RBC morphology, including features like microcytosis, macrocytosis, anisocytosis and hypochromia.

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