This retrospective, descriptive, and analytical study was conducted over a six-month period (January to June 2025) at the Cuomo Cardiac Center in Dakar, involving 39 consecutive adult patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Perioperative data were extracted from medical records, supplemented by systematic arterial blood gas analysis within the first six postoperative hours. Statistical analysis was performed using Sphinx Plus software. Results revealed a high prevalence of acid-base disorders (ABD) at 64.1% (25 patients). Acidosis was largely predominant (56.4%), categorized as respiratory (33.3%), metabolic (15.4%), and mixed (7.7%), while alkalosis remained marginal (7.7%). The study identified the intraoperative use of two or more sympathomimetic agents as a major risk factor, strongly correlated with the occurrence of an ABD (p = 0.005). Regarding prognosis, patients with an ABD had a significantly longer mean length of stay in the intensive care unit (4.76 days vs. 3.43 days). Finally, although the sample size limited statistical significance for certain variables, the impact on mortality was notable: all four recorded deaths (10.3%) occurred exclusively in acidotic patients. These findings underscore the imperative for increased monitoring and early correction of imbalances, particularly in patients requiring heavy hemodynamic support.
Ba et al. (Fri,) studied this question.