What question did this study set out to answer?

This research aims to identify the risk factors for major gastrointestinal bleeding (MGB) in septic patients.

March 4, 2026

Risk factors for major gastrointestinal bleeding in septic patients: a multicenter retrospective study.

Key Points

This research aims to identify the risk factors for major gastrointestinal bleeding (MGB) in septic patients.
Multicenter retrospective design
Analysis of patient data from multiple hospitals
Examination of correlations between MGB and various clinical factors
MGB occurred in 2.0% of septic patients but was linked to significantly higher mortality rates.
Older age and renal dysfunction were significant risk factors.
Elevated BUN levels and gastrointestinal sources were key drivers of risk.
Urinary tract infection was associated with lower risk of MGB.

Abstract

Although MGB occurred in only 2.0% of septic patients, it was associated with substantially higher mortality. Older age, renal dysfunction, elevated BUN and gastrointestinal sources were key drivers of risk, while urinary tract infection was associated with a lower risk. These findings underscore the importance of early risk stratification and targeted preventive strategies in high-risk patients to mitigate bleeding events and improve survival.

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Authors

Yi Zhang

Heng Zhang

Qingdao University

Yuanyuan Feng

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Institutions

Shanghai Jiao Tong University

Huazhong University of Science and Technology

Army Medical University

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Risk factors for major gastrointestinal bleeding in septic patients: a multicenter retrospective study.

Key Points

Abstract

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Authors

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