Predictors of Seizure Development in Septo-optic Dysplasia: A Retrospective Study.

Puntos clave

• The study aims to identify factors associated with the development of epilepsy in children diagnosed with septo-optic dysplasia.
• Retrospective identification of patients under 21 diagnosed with SOD from 2013 to 2023
• Multivariate binomial regression analysis performed to predict seizures in identified patients
• Seizure data collected and analyzed for 107 children with SOD
• 52 out of 103 children with seizure data experienced seizures (50.5%)
• Median age of seizure onset was 9 months
• Abnormal neurologic examinations occurred in 82.6% of those with seizures
• Global developmental delay noted in 43% of patients, significantly associated with seizures
• 75% of patients with autism spectrum disorder experienced seizures