District hospitals in Ethiopia play a crucial role in healthcare delivery, but their effectiveness is often questioned due to methodological weaknesses. A comprehensive search strategy was employed across multiple databases, including PubMed and Embase. Studies were included if they utilised quasi-experimental designs to measure risk reduction outcomes in Ethiopian district hospitals from to. Methodological quality was assessed using the Cochrane Risk of Bias Tool. A total of 47 studies met inclusion criteria, with a majority (89%) employing interrupted time series designs. While there is evidence suggesting improved outcomes in some areas, methodological weaknesses such as lack of blinding and inadequate control groups were common. The review underscores the need for more rigorous methodological approaches to ensure reliable results from quasi-experimental studies in Ethiopian district hospitals. Future research should prioritise robust design features like randomization controls, detailed baseline data collection, and transparent reporting guidelines to enhance study validity. Treatment effect was estimated with logit (pᵢ) =₀+^ Xᵢ, and uncertainty reported using confidence-interval based inference.
Negash et al. (Sat,) studied this question.