What question did this study set out to answer?

The research aims to identify effective management strategies for neonatal limb ischaemia (NLI).

March 5, 2026

Management of neonatal limb ischaemia: experience from a UK tertiary children’s hospital

Key Points

The research aims to identify effective management strategies for neonatal limb ischaemia (NLI).
Review of cases managed at a UK tertiary children's hospital
Assessment of treatment outcomes following anticoagulation and adjunctive therapies
Development of a treatment algorithm for clinical decision-making
Most NLI cases were successfully managed with anticoagulation
Higher-risk neonates required interventions like thrombolysis or surgery when collateral circulation was poor
Early involvement of a multidisciplinary team improved patient outcomes

Abstract

Most cases of NLI can be managed successfully with prompt anticoagulation and adjunctive therapy. Neonates with occlusive arterial thrombosis and poor collateral circulation represent the highest-risk group and may require escalation to thrombolysis or surgery. Early multidisciplinary involvement is essential. An evidence-based treatment algorithm is presented to support clinical decision-making.

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Discussion

Authors

Ibrahim Natalwala

Ingrid Kieran

Chiraag Thakrar Karia

Journals

Journal of Hand Surgery (European Volume)

Actions

Institutions

University of Leeds

Leeds General Infirmary

Great North Children's Hospital

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Management of neonatal limb ischaemia: experience from a UK tertiary children’s hospital

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study