Neutrophil Gelatinase-Associated Lipocalin and Neutrophil-to-Lymphocyte Ratio as Indicators of Nephropathy in Type 2 Diabetic Mellitus Patients in Ghana: A Case-Control Study.

Key Points

• This research aims to assess the effectiveness of sNGAL and NLR in identifying nephropathy in individuals with type 2 diabetes in Ghana.
• Conducted a case-control study comparing levels of sNGAL and NLR among type 2 diabetes patients and healthy controls.
• Measured serum neutrophil gelatinase-associated lipocalin (sNGAL) and calculated neutrophil-to-lymphocyte ratio (NLR).
• Analyzed the discrimination ability of both markers for diabetic nephropathy.
• sNGAL demonstrated superior reliability as an indicator of nephropathy compared to NLR.
• NLR showed no significant difference between groups, indicating it is not a trustworthy marker for diabetic nephropathy.
• sNGAL is recommended for monitoring nephropathy in type 2 diabetes patients.