What question did this study set out to answer?

This research aims to evaluate the prognostic value of the Node-RADS scoring system in stage IIICr cervical cancer.

March 5, 2026Open Access

Prognostic value of Node-RADS scoring in stage IIICr cervical cancer: development and validation of novel nomograms

LJLi JiangGuangxi Medical University SMShanshan MaGuangxi Medical University QDQinghua DuGuangxi Medical University

Key Points

This research aims to evaluate the prognostic value of the Node-RADS scoring system in stage IIICr cervical cancer.
Developed a nomogram using Node-RADS scores along with clinicopathological data and therapies
Compared the nomogram's performance against FIGO staging
Analyzed correlations between Node-RADS scores and patient survival outcomes
Nomogram showed superior discriminative ability over FIGO staging
Higher Node-RADS scores correlated with worse survival outcomes
Lymph node irradiation of ≥ 60 Gy EQD2 associated with potential survival benefits

Abstract

The nomogram incorporating the Node-Reporting and Data System (Node-RADS) score can serve as a potential prognostic marker to assist clinicians. The nomogram incorporating the Node-RADS score, which integrated clinicopathological data and therapies, outperformed Federation of Obstetrics and Gynecology (FIGO) staging in discriminative ability and clinical utility. Higher Node-RADS scores correlated with worse survival outcomes of patients, and lymph node (LN) boost irradiation ≥ 60 Gy EQD2 might provide survival benefits.

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