Recyclization of 5-Aryl-1H-pyrrole-2,3-diones under the Action of Amidoximes. Synthesis of Enamines with a 1,2,4-Oxadiazole Moiety

Key Points

• The aim is to explore the recyclization of 5-aryl-1H-pyrrole-2,3-diones using amidoximes to synthesize enamines with a 1,2,4-oxadiazole moiety.
• Reacted 5-aryl-1H-pyrrole-2,3-diones with amidoximes.
• Focused on the recyclization process under specific conditions.
• Utilized 1,4-binucleophilic reagents for the reaction.
• Successfully synthesized enamines containing a 1,2,4-oxadiazole fragment.
• Confirmed that the reaction is the first example of this recyclization type for the target compounds.