Synthesis demonstrates the formation of enamines in 5-aryl-1H-pyrrole-2,3-diones, indicating new 1H-pyrrole precursors.
5-Aryl-1Н-pyrrole-2,3-diones react with amidoximes to form enamines with a 1,2,4-oxadiazole fragment, which are potential precursors of a new type of 1Н-pyrrole-2,3-diones. The described reaction is the first example of the recyclization of 4-unsubstituted 5-aryl-1H-pyrrole-2,3-diones under action of 1,4-binucleophilic reagent.
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A. N. Maslivets (2025) studied this question.
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