A chitosan-based thermosensitive hydrogel incorporating propranolol nanoparticles to promote early osseointegration and peri-implant soft-tissue healing

Key Points

• The aim is to assess the impact of a chitosan-based hydrogel with propranolol on osseointegration and tissue healing.
• Developed a chitosan-based thermosensitive hydrogel
• Incorporated propranolol nanoparticles into the hydrogel
• Assessed the hydrogel's effects on peri-implant soft-tissue and osseointegration
• The propranolol-loaded hydrogel enhanced osseointegration rates
• Promoted improved healing of the gingival tissue around implants