260eP Solitary fibrous tumour patterns of presentation and treatment outcomes: Insights from a tertiary care centre

Background: Bone sarcomas are rare and heterogeneous malignant tumors, posing significant challenges in diagnosis and management.While substantial progress has been made in the early detection and treatment of cancer, the prognosis for patients with bone sarcomas has remained largely unchanged.This retrospective study aims to examine the survival rates of Moroccan patients with bone sarcomas and to investigate prognostic factors.Methods: Patients with pathologically confirmed primary malignant bone sarcomas diagnosed between January 2012 and January 2024 were retrospectively reviewed at the National Institute of Oncology.As medical treatment for patients 15 years were included.Exclusion criteria were non-sarcomatous bone tumors, metastatic lesions, lymphomas involving bone, and giant cell tumors.Clinical and treatment data were collected from medical records.Overall survival (OS) was estimated using the Kaplan-Meier method.Prognostic factors were explored using Cox regression; variables with a p-value 8 cm (HR 3.62, p=0.002), and presence of distant metastases at diagnosis (HR 3.65, 95% CI 1.69-7.90,p=0.001) were independent predictors of poor survival. Conclusions:Primary bone sarcomas remain a clinical challenge, largely due to delayed diagnosis and limited access to specialized expertise.This study offers an overview of the epidemiological patterns and survival outcomes associated with these tumors.