ABSTRACT The oxygen‐dependent enzyme, succinic dehydrogenase (SDH) was studied in the corneal epithelium of rabbits exposed to selected oxygen environments for specific periods of time. Oxygen atmospheres of 3% or less for a period of five hours caused greater than normal SDH reactivity, as did oxygen deprivation for five hours. Decreased SDH reactivity could be provoked as well by selected conditions. The histochemical procedure used here has application in studying new contact lens materials and the toxic effects of drugs and irritants on the corneal epithelium as well.
Hill et al. (Wed,) studied this question.
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