Individuals at risk for obstructive sleep apnea had a significantly higher mean arterial pressure (99.6 mm Hg) compared to those at low risk (93.9 mm Hg) among apparently healthy adults.
Cross-Sectional (n=144)
No
Does obstructive sleep apnea risk associate with elevated mean arterial pressure in apparently healthy adults?
In apparently healthy adults, being at risk for obstructive sleep apnea is independently associated with elevated mean arterial pressure, suggesting it may serve as an early marker for subclinical cardiovascular risk.
Effect estimate: Cohen's d 0.531
Absolute Event Rate: 99.6% vs 93.9%
p-value: p=0.021
Background: Obstructive sleep apnea (OSA) has emerged as a significant public health concern in South India, with mounting evidence linking it to cardiovascular complications, including elevated mean arterial pressure (MAP).The STOP-BANG questionnaire provides a validated, noninvasive screening approach for OSA risk assessment in resource-limited settings.However, the association between OSA risk and MAP in apparently healthy South Indian adults remains inadequately characterized.Materials and methods: We conducted a cross-sectional study among 144 apparently healthy adults (aged 18-65 years) accompanying patients to a tertiary care hospital in South India.Obstructive sleep apnea risk was assessed using the STOP-BANG questionnaire and categorized as low risk (score 2) or at risk (score > 2).Demographic and anthropometric data were collected, and MAP was calculated from standardized blood pressure (BP) measurements.Statistical analysis included independent t-tests and multiple linear regression to identify independent predictors of MAP, adjusting for alcohol use and smoking status.Results: The prevalence of OSA risk was 16.0% (n = 23).The MAP was significantly higher in the at-risk group than in the low-risk group (99.6 10.2 vs 93.9 10.8 mm Hg, p = 0.021, Cohen's d = 0.531).After adjusting for alcohol use and smoking status, OSA risk remained independently associated with elevated MAP ( = 0.476, 95% CI: 0.551-9.830,p = 0.029).This association demonstrated a moderate effect size, suggesting clinical relevance. Conclusion:Obstructive sleep apnea risk is independently associated with elevated MAP in apparently healthy South Indian adults.These findings suggest that OSA risk screening may identify individuals with subclinical cardiovascular risk, providing opportunities for early intervention and prevention of hypertension.
Sanjana et al. (Wed,) conducted a cross-sectional in Obstructive Sleep Apnea risk (n=144). At risk for OSA (STOP-BANG score > 2) vs. Low risk for OSA (STOP-BANG score ≤ 2) was evaluated on Mean Arterial Pressure (MAP) (Cohen's d 0.531, p=0.021). Individuals at risk for obstructive sleep apnea had a significantly higher mean arterial pressure (99.6 mm Hg) compared to those at low risk (93.9 mm Hg) among apparently healthy adults.