Background Basal cell carcinoma (BCC) is the most common skin cancer worldwide. However, it is relatively uncommon in noncraniofacial areas. Objective To analyse the clinical and pathological features of Chinese patients with noncraniofacial BCC. Methods We retrospectively analysed the clinical data of 305 patients with BCC admitted to the Department of Dermatology of Beijing Chao‐Yang Hospital, Capital Medical University, from January 2020 to December 2024. Following strict selection criteria, 73 patients were included in this study. We statistically analysed patient demographics, disease duration, lesion characteristics, treatment modalities and pathological subtypes. Results Seventy‐three cases of noncraniofacial BCC were identified, accounting for 23.93% of all cases. The average patient age was 64.29 years, with a peak incidence in the 70–79 age group (24, 32.88%) and a male‐to‐female ratio of 0.74:1. The most commonly affected site was the trunk (27, 37.0%), followed by the perineal area (15, 20.5%). The limbs and axillae were also affected. Histopathologically, the nodular (38, 52.1%) and superficial (29, 39.7%) subtypes predominated. Conclusions Noncraniofacial BCC accounts for 23.93% of all BCC cases in our Chinese cohort and predominantly affects elderly female patients (peak age: 70–79 years; M:F = 0.74:1). The trunk (37.0%) and perineal area (20.5%) were the most common sites, with the nodular (52.1%) and superficial subtypes (39.7%) predominating histopathologically. These findings emphasize the importance of comprehensive screening for noncraniofacial lesions and timely skin biopsy to prevent misdiagnosis. They also provide valuable clinical references for the management of this specific subgroup of BCC in Chinese patients.
Tan et al. (Thu,) studied this question.
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